Eriksson U J
Department of Medical Cell Biology, Uppsala University, Sweden.
Diabetologia. 1996 Sep;39(9):1123-5. doi: 10.1007/BF00400664.
Dr. Phillips argues that insulin resistance in adult life may be the price the developing fetus has to pay in return for a short-term successful adaptation to undernutrition in utero. The concept is interesting, and, indeed, challenging. There is, however, a strong need for expansion of the existing knowledge of the possible developmental mechanisms involved, especially against the background of the obvious diagnostic and therapeutic gains in this particular group of patients.
菲利普斯博士认为，成年后的胰岛素抵抗可能是发育中的胎儿为了短期成功适应子宫内营养不良而必须付出的代价。这一概念很有趣，而且确实具有挑战性。然而，迫切需要扩展关于可能涉及的发育机制的现有知识，尤其是在这一特定患者群体有明显诊断和治疗进展的背景下。
