Andersen W K, Rao B K, Bhawan J
Department of Dermatology, Boston University School of Medicine, Massachusetts, USA.
Am J Dermatopathol. 1996 Aug;18(4):364-6. doi: 10.1097/00000372-199608000-00006.
We describe four cases of unusual superficial cutaneous cysts that have a lining epithelium composed of apocrine cells immediately adjacent to keratinizing squamous epithelium with an intact granular layer. Two of the cysts were on the nipple of the breast and two of the cysts were on the face. The lumina of all four cysts contained keratin. Immunoperoxidase staining for carcinoembryonic antigen in the facial cysts showed positive staining within the apocrine cells of the lining epithelium in one case. The pathogenesis of these lesions is uncertain. We suggest that these unusual cysts be called hybrid epidermoid and apocrine cysts.
我们描述了4例不寻常的浅表皮肤囊肿，其衬里上皮由顶泌汗腺细胞组成，紧邻具有完整颗粒层的角化鳞状上皮。其中2例囊肿位于乳房乳头，2例位于面部。所有4例囊肿的腔内均含有角蛋白。面部囊肿癌胚抗原免疫过氧化物酶染色显示，1例衬里上皮的顶泌汗腺细胞内呈阳性染色。这些病变的发病机制尚不确定。我们建议将这些不寻常的囊肿称为混合性表皮样和顶泌汗腺囊肿。
