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瑞氏综合征：患者血清在体外会改变线粒体功能和形态。

Reye's syndrome: patient serum alters mitochondrial function and morphology in vitro.

作者信息

Aprille J R

出版信息

Science. 1977 Aug 26;197(4306):908-10. doi: 10.1126/science.887930.

DOI:10.1126/science.887930
PMID:887930
Abstract

A direct relationship between a putative Reye's syndrome "serum factor" and generalized mitochondrial damage has been demonstrated in vitro. The clinical features of Reye's syndrome may be secondary to disrupted mitochondrial structure and a consequent impairment of energy-linked functions involving many organs.

摘要

在体外已证实假定的瑞氏综合征“血清因子”与全身性线粒体损伤之间存在直接关系。瑞氏综合征的临床特征可能继发于线粒体结构破坏以及随之而来的涉及多个器官的能量相关功能受损。

相似文献

1
Reye's syndrome: patient serum alters mitochondrial function and morphology in vitro.瑞氏综合征：患者血清在体外会改变线粒体功能和形态。
Science. 1977 Aug 26;197(4306):908-10. doi: 10.1126/science.887930.
2
Reye's syndrome: the effect of patient serum on mitochondrial respiration in vitro.瑞氏综合征：患者血清对体外线粒体呼吸的影响。
Biochem Biophys Res Commun. 1977 Dec 21;79(4):1122-9. doi: 10.1016/0006-291x(77)91122-6.
3
Identification of the Reye's syndrome "serum factor".瑞氏综合征“血清因子”的鉴定
Biochem Biophys Res Commun. 1980 May 14;94(1):381-9. doi: 10.1016/s0006-291x(80)80232-4.
4
Reye's syndrome: mitochondrial swelling and Ca2+ release induced by Reye's plasma, allantoin, and salicylate.瑞氏综合征：瑞氏血浆、尿囊素和水杨酸盐诱导的线粒体肿胀及钙离子释放。
Arch Biochem Biophys. 1986 Feb 1;244(2):773-86. doi: 10.1016/0003-9861(86)90646-6.
5
Reye's syndrome: plasma-induced alterations in mitochondrial structure and function.瑞氏综合征：血浆诱导的线粒体结构和功能改变。
Arch Biochem Biophys. 1982 Apr 1;214(2):522-30. doi: 10.1016/0003-9861(82)90056-x.
6
Effect of Reye's syndrome serum on the ultrastructure of isolated liver mitochondria.
Lab Invest. 1989 Apr;60(4):568-73.
7
Inhibition of mitochondrial functions by margosa oil: possible implications in the pathogenesis of Reye's syndrome.印度楝树油对线粒体功能的抑制作用：对瑞氏综合征发病机制的潜在影响。
Pediatr Res. 1987 Aug;22(2):184-7. doi: 10.1203/00006450-198708000-00017.
8
Ammonium inhibition of fatty acid oxidation in rat liver mitochondria. A possible cause of fatty liver in Reye's syndrome and urea cycle defects.铵对大鼠肝线粒体脂肪酸氧化的抑制作用。雷氏综合征和尿素循环缺陷中脂肪肝的一个可能原因。
Biochem Biophys Res Commun. 1985 Mar 15;127(2):565-70. doi: 10.1016/s0006-291x(85)80197-2.
9
Effect of Reye's syndrome serum on isolated chinchilla liver mitochondria.瑞氏综合征血清对离体龙猫肝线粒体的影响。
J Clin Invest. 1985 Aug;76(2):816-25. doi: 10.1172/JCI112039.
10
Biochemical relationships between Reye's and Reye's-like metabolic and toxicological syndromes.瑞氏综合征及类瑞氏代谢与毒理学综合征之间的生化关系。
Med Toxicol Adverse Drug Exp. 1989 Jul-Aug;4(4):272-94. doi: 10.1007/BF03259913.

引用本文的文献

1
Application of trace metal analysis to basic problems in neurobiology studies of patients with Reye's syndrome.痕量金属分析在瑞氏综合征患者神经生物学研究基础问题中的应用。
Biol Trace Elem Res. 1987 Aug;13(1):55-67. doi: 10.1007/BF02796621.
2
Reye's syndrome: a clinical review.瑞氏综合征：临床综述
Can Med Assoc J. 1981 Feb 15;124(4):375-82, 425.
3
Effect of Reye's syndrome serum on isolated chinchilla liver mitochondria.瑞氏综合征血清对离体龙猫肝线粒体的影响。
J Clin Invest. 1985 Aug;76(2):816-25. doi: 10.1172/JCI112039.
4
Biochemical relationships between Reye's and Reye's-like metabolic and toxicological syndromes.瑞氏综合征及类瑞氏代谢与毒理学综合征之间的生化关系。
Med Toxicol Adverse Drug Exp. 1989 Jul-Aug;4(4):272-94. doi: 10.1007/BF03259913.
5
Salicylates and proton transport through lipid bilayer membranes: a model for salicylate-induced uncoupling and swelling in mitochondria.水杨酸盐与质子通过脂质双分子层膜的转运：水杨酸盐诱导线粒体解偶联和肿胀的模型
J Membr Biol. 1990 May;115(3):253-60. doi: 10.1007/BF01868640.
6
Aspirin, acetaminophen and proton transport through phospholipid bilayers and mitochondrial membranes.阿司匹林、对乙酰氨基酚与质子通过磷脂双层膜和线粒体膜的转运。
Mol Cell Biochem. 1992 Sep 8;114(1-2):3-8. doi: 10.1007/BF00240290.