Lau K W, Ding Z P, Gao W, Koh T H, Johan A
Singapore Heart Centre, Singapore.
Eur Heart J. 1996 Sep;17(9):1367-72. doi: 10.1093/oxfordjournals.eurheartj.a015071.
Although the efficacy of percutaneous balloon mitral valvuloplasty in patients with unoperated mitral stenosis has been well documented, there exists less clear-cut data on its effectiveness in patients with mitral restenosis after previous surgical commissurotomy. Accordingly, the purpose of this study was to evaluate our immediate and midterm results of balloon mitral valvuloplasty in this subset of patients with previous mitral surgery.
Between October 1991 and August 1995, 29 consecutive patients with mitral restenosis after prior surgical commissurotomy (group 1) underwent Inoue balloon mitral valvuloplasty. They were matched on a patient-to-patient basis with regard to baseline mitral echocardiographic score mitral valve area, severity of angiographic mitral regurgitation and follow-up duration with 29 other patients with unoperated mitral stenosis (group 2) who underwent balloon mitral valvuloplasty during the same study period.
Balloon mitral valvuloplasty yielded identical improvements in transmitral gradient and mitral valve area (from 0.8 to 1.6 cm2) determined echocardiographically, and similar changes in the severity of mitral regurgitation in both groups of patients. All procedures were successfully completed without major cardiac complications. Follow-up echocardiographic assessment in 73% of patients revealed equal mitral valve area (1.6 cm2) and a restenosis rate of 17%, with no difference in the restenosis rate between the two groups.
Balloon mitral valvuloplasty in selected patients with mitral restenosis after past surgical commissurotomy can be performed safely and with similar immediate and midterm efficacy as in patients with de novo mitral stenosis.
尽管经皮球囊二尖瓣成形术治疗未经手术的二尖瓣狭窄患者的疗效已有充分记录,但对于该手术在既往外科二尖瓣交界切开术后二尖瓣再狭窄患者中的有效性,相关数据尚不明确。因此,本研究旨在评估球囊二尖瓣成形术治疗这部分既往有二尖瓣手术史患者的近期和中期结果。
1991年10月至1995年8月,连续29例既往外科二尖瓣交界切开术后二尖瓣再狭窄患者(1组)接受了Inoue球囊二尖瓣成形术。将他们与同期接受球囊二尖瓣成形术的另外29例未经手术的二尖瓣狭窄患者(2组)按患者个体情况进行匹配,匹配因素包括二尖瓣超声心动图基线评分、二尖瓣瓣口面积、血管造影显示的二尖瓣反流严重程度及随访时间。
两组患者经超声心动图测定的跨二尖瓣压差和二尖瓣瓣口面积(从0.8增至1.6cm²)均有相同程度改善,二尖瓣反流严重程度变化相似。所有手术均成功完成,无重大心脏并发症。73%的患者随访超声心动图评估显示二尖瓣瓣口面积相同(1.6cm²),再狭窄率为17%,两组再狭窄率无差异。
对于既往外科二尖瓣交界切开术后二尖瓣再狭窄的特定患者,球囊二尖瓣成形术可安全实施,近期和中期疗效与初发性二尖瓣狭窄患者相似。