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[甲状腺制剂与抗甲状腺制剂的联合应用]

[Joint use of thyroid and antithyroid preparations].

作者信息

Beskrovnyĭ A M, Sukacheva O A

出版信息

Vopr Onkol. 1979;25(5):17-20.

PMID:88805
Abstract

On the model of the mammary gland cancer, induced by a carcinogen in rats, it is shown that thyroxine (in a dose approximately equal to the physiological one, which per se would stimulate neoplasia or renders no effect) increases the antineoplastic action of the thyroid function inhibitors when administered simultaneously. Thus, they may be considered a positive compensation factor. Simultaneous application of the thyroid hormone with a hypolipidemic preparation--cetamiphene seems to be mostly advantageous.

摘要

在大鼠中由致癌物诱发乳腺癌的模型上显示,甲状腺素(剂量约等于生理剂量,其本身会刺激肿瘤形成或无作用)与甲状腺功能抑制剂同时给药时,会增强其抗肿瘤作用。因此,甲状腺素可被视为一种积极的补偿因素。甲状腺激素与降血脂制剂西他米芬同时应用似乎最为有利。

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