外周关节骨关节炎易感性中的妇产科因素。
Obstetric and gynaecological factors in susceptibility to peripheral joint osteoarthritis.
作者信息
Silman A J, Newman J
机构信息
ARC Epidemiology Research Unit, University of Manchester, United Kingdom.
出版信息
Ann Rheum Dis. 1996 Sep;55(9):671-3. doi: 10.1136/ard.55.9.671.
Abstract
There is clear evidence that the age period coinciding with the peak age of the menopause is associated with an increased prevalence of osteoarthritis and this fits in with clinical observation of high likelihood of presentation at this age. A number of pieces of biological evidence also support the notion that changes in sex hormone status might influence risk of degenerative disease at peripheral joint sites. There do not appear, however, to be any important epidemiological predictors based on menstrual or obstetric history that might be useful in predicting who these women might be.
摘要
有明确证据表明，与绝经高峰期年龄相符的年龄段与骨关节炎患病率增加相关，这与该年龄段发病可能性高的临床观察结果相符。一些生物学证据也支持这样的观点，即性激素状态的变化可能会影响外周关节部位退行性疾病的风险。然而，基于月经史或产科病史，似乎没有任何重要的流行病学预测指标可用于预测哪些女性可能患病。
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