Massoud T F, Ji C, Guglielmi G, Viñuela F
Endovascular Therapy Service, Department of Radiological Sciences, University of California, Los Angeles Medical Center 90024, USA.
AJNR Am J Neuroradiol. 1996 Sep;17(8):1459-66.
The technical feasibility of selective intranidal endovascular occlusion of experimental arteriovenous malformations with detachable superfine platinum electrodes was assessed in a swine model. The delivery and release of electrodes were performed within normal carotid retia mirabilia, the faster-flowing nidus (bilateral retia) of a carotid-jugular fistula-type model of an arteriovenous malformation, and a small-caliber H-type direct arteriovenous fistula. Controllable atraumatic placement of the electrodes was possible deep within each rete and in the middle of the fistula. The devices were soft and flexible, allowing them to conform to the tight turns and branches of rete vessels. Marked diminution of flow was achieved by release of multiple devices within each rete. Migration of the electrode occurred when detached within the larger-caliber arteriovenous fistula. The main advantages of this technique appear to be the controlled delivery and assured release of an occlusive radiopaque embolic agent within the nidus.
在猪模型中评估了使用可分离超细铂电极对实验性动静脉畸形进行选择性巢内血管内闭塞的技术可行性。电极的输送和释放是在正常的颈动脉奇网、动静脉畸形的颈动脉 - 颈静脉瘘型模型中血流较快的巢（双侧奇网）以及小口径H型直接动静脉瘘中进行的。电极能够在每个奇网深处和瘘管中部进行可控的无创伤放置。这些装置柔软且灵活，能够顺应奇网血管的急转弯和分支。通过在每个奇网内释放多个装置，实现了血流的显著减少。当电极在较大口径的动静脉瘘内分离时会发生迁移。该技术的主要优点似乎是能够在巢内可控地输送并确保释放不透射线的闭塞性栓塞剂。
