Massoud T F, Ji C, Viñuela F, Guglielmi G, Robert J, Duckwiler G R, Gobin Y P
Department of Radiological Sciences, University of California at Los Angeles Medical Center 90024.
AJNR Am J Neuroradiol. 1994 Sep;15(8):1537-45.
We assessed the feasibility of creating an experimental arteriovenous malformation model in swine by diverting and increasing blood flow through bilateral retia mirabilia. This was achieved by surgical formation of a large right-sided carotid-jugular fistula, in combination with endovascular occlusion of several neck arteries ipsilateral to the fistula. Using this technique, 11 of 13 swine demonstrated an acute-phase angiographic simulation of an arteriovenous malformation. There was rapid circulatory diversion from the left ascending pharyngeal artery ("feeder"), across both retia ("nidus"), and fast retrograde flow into the right ascending pharyngeal and common carotid arteries ("draining vein") toward the fistula. The relevant vascular anatomy of the swine head and neck is outlined, and steps in the construction of this arteriovenous malformation model are detailed.
我们评估了通过分流并增加流经双侧奇静脉网的血流量，在猪身上创建实验性动静脉畸形模型的可行性。这是通过手术形成一个大型右侧颈总动脉 - 颈静脉瘘，并结合对瘘同侧的几条颈部动脉进行血管内闭塞来实现的。使用该技术，13头猪中有11头在急性期血管造影中呈现出动静脉畸形的模拟情况。有快速的循环分流，从左咽升动脉（“供血动脉”），穿过双侧奇静脉网（“病灶”），并快速逆行流入右咽升动脉和颈总动脉（“引流静脉”），朝向瘘口。文中概述了猪头颈部的相关血管解剖结构，并详细介绍了该动静脉畸形模型构建的步骤。
