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患有和未患有普拉德-威利综合征的个体的食物偏好。

Food preferences among individuals with and without Prader-Willi syndrome.

作者信息

Glover D, Maltzman I, Williams C

机构信息

Department of Psychology, University of California, Los Angeles 90024, USA.

出版信息

Am J Ment Retard. 1996 Sep;101(2):195-205.

PMID:8883673
Abstract

Eleven individuals with Prader-Willi syndrome and 10 control subjects who had mental retardation due to other causes (with and without overeating histories) participated in two experiments on food preferences. They gave preference rankings for various foods, then chose between a small amount of their most preferred food and an alternative choice of a larger amount of mixed-preference foods (Experiment 1) or an alternative choice of a larger amount of their least preferred food (Experiment 2). Unlike overweight-prone control subjects who selected sweet food over a larger quantity of unpreferred food, subjects with Prader-Willi syndrome selected preferred items only over least-preferred items (Experiment 2) but not over mixed-preference items (Experiment 1). Implications for treatment were discussed.

摘要

11名普拉德-威利综合征患者以及10名因其他原因导致智力发育迟缓的对照受试者(有或无暴饮暴食史)参与了两项关于食物偏好的实验。他们对各种食物给出偏好排名,然后在少量他们最喜欢的食物与大量混合偏好食物的替代选择(实验1)或大量他们最不喜欢的食物的替代选择(实验2)之间进行选择。与倾向于超重的对照受试者不同,后者会选择甜食而非大量不喜欢的食物,而普拉德-威利综合征患者仅在最不喜欢的食物中选择偏好的食物(实验2),但在混合偏好食物中不会这样做(实验1)。文中讨论了该研究结果对治疗的启示。

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Calorie seeking, but not hedonic response, contributes to hyperphagia in a mouse model for Prader-Willi syndrome.在普拉德-威利综合征小鼠模型中,热量寻求而非享乐反应导致了食欲亢进。
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Food-related neural circuitry in Prader-Willi syndrome: response to high- versus low-calorie foods.普拉德-威利综合征中与食物相关的神经回路:对高热量与低热量食物的反应。
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