Shanygina K I, Novikova N A
Vopr Med Khim. 1977 May-Jun(3):358-60.
Administration of toxic doses of noradrenaline into rats led to exhaustion of noradrenaline reserves in liver and heart tissues with the simultaneous increase in the activity of glucose-6-phosphate dehydrogenase in the tissues. Actinomycin D, administered together with noradrenaline, completely prevented the elevation of the G6PD activity in the tissues studied. The data obtained suggest that sympathetic nervous system and its mediator are responsible for regulation of the rate of enzymatic protein synthesis in tissues.
给大鼠注射中毒剂量的去甲肾上腺素会导致肝脏和心脏组织中的去甲肾上腺素储备耗尽，同时这些组织中葡萄糖-6-磷酸脱氢酶的活性增加。与去甲肾上腺素一起注射的放线菌素D完全阻止了所研究组织中G6PD活性的升高。所得数据表明，交感神经系统及其介质负责调节组织中酶蛋白的合成速率。
