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[糖尿病兔渗出液白细胞中UDPG-糖原转移酶的两种形式]

[2 forms of UDPG-glycogen transferase in leukocytes of rabbit exudate in diabetes].

作者信息

Shestakova S A

出版信息

Vopr Med Khim. 1977 May-Jun(3):404-7.

PMID:888408
Abstract

UDPG-glycogen transferase existed mainly as D-form, depending on glucose-6-phosphate, and in minority as E-form in leukocytes of exudate of rabbits with diabetes and of control animals. The total enzymatic activity as well as the activity of D-form were almost the same both in leukocytes under diabetes and in control. The E-form activity accounted for 18% of the total enzymatic activity in leukocytes of diabetic rabbits and for 14% in leukocytes of control animals. Preliminary incubation of leukocyte homogenates at 37 degrees for 30 min led to decrease in the relation between the enzyme forms both in control rabbits and in animals with diabetes.

摘要

UDPG-糖原转移酶主要以D型存在,依赖于6-磷酸葡萄糖,在糖尿病兔和对照动物渗出液白细胞中少数以E型存在。糖尿病状态下白细胞和对照白细胞中的总酶活性以及D型活性几乎相同。E型活性在糖尿病兔白细胞中占总酶活性的18%,在对照动物白细胞中占14%。将白细胞匀浆在37℃预孵育30分钟导致对照兔和糖尿病动物中酶形式之间的比例均下降。

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