Tumilasci O R, Arqueros M C, Ostuni M A, el Tamer E, Houssay A B
Department of Physiology, Faculty of Medicine, University of Buenos Aires, Argentina.
J Endocrinol Invest. 1996 Jul-Aug;19(7):412-4. doi: 10.1007/BF03349884.
Parotid saliva was collected with a Carlson-Crittenden device, under citric acid stimulation, in 18 patients with autoimmune thyroid disease. Thyrotropin Receptor Antibodies (TRAb) were measured with a radioreceptor assay in parotid saliva and in serum in the same patients, and a statistical analysis of the data was performed. TRAb levels in parotid saliva were higher than in serum in the 3 pathologies studied (Graves' disease, Hashitoxicosis and Hashimoto's thyroiditis). There was good correlation between salivary and serum levels.
在柠檬酸刺激下,使用卡尔森 - 克里滕登装置收集了18例自身免疫性甲状腺疾病患者的腮腺唾液。用放射受体分析法测定了同一批患者腮腺唾液和血清中的促甲状腺素受体抗体(TRAb),并对数据进行了统计分析。在所研究的三种疾病(格雷夫斯病、甲状腺毒症和桥本甲状腺炎)中,腮腺唾液中的TRAb水平高于血清中的水平。唾液和血清水平之间存在良好的相关性。