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单侧隐睾症后的父子关系:一项对照研究。

Paternity after unilateral cryptorchidism: a controlled study.

作者信息

Lee P A, O'Leary L A, Songer N J, Coughlin M T, Bellinger M F, LaPorte R E

机构信息

Department of Pediatrics, University of Pittsburgh School of Medicine, Children's Hospital of Pittsburgh, PA 15213-2583, USA.

出版信息

Pediatrics. 1996 Oct;98(4 Pt 1):676-9.

PMID:8885945
Abstract

OBJECTIVE

To determine if paternity is decreased among formerly unilateral cryptorchid men compared with a control group of men.

SUBJECTS AND METHODS

Formerly unilateral cryptorchid men who had orchiopexy between 1955 and 1971 at the Children's Hospital of Pittsburgh and a group of control men have had their medical records reviewed and have been surveyed by questionnaire.

RESULTS

Among the men who had ever married and had attempted paternity, significantly more of the unilateral cryptorchid men had been unable to father children (10.5%) than among the control group (5.4%). No difference was found when the groups were compared for the duration of regular intercourse without contraception to conception of their first child. There was no relationship between the age of orchiopexy or lifestyle factors and paternity or between the age of orchiopexy and months of regular unprotected intercourse to conception. Paternity among both groups was related to female-related infertility factors and to the presence of varicoceles.

CONCLUSION

When compared with a control group, paternity was compromised after unilateral cryptorchidism. Infertility is about twice as frequent among the unilateral group. There was no evidence of subfertility requiring a longer exposure of regular intercourse without contraception among the fertile subgroup. No correlation was found between age of orchiopexy and paternity.

摘要

目的

确定与对照组男性相比,既往单侧隐睾男性的生育能力是否降低。

研究对象与方法

对1955年至1971年期间在匹兹堡儿童医院接受过睾丸固定术的既往单侧隐睾男性以及一组对照男性的病历进行了回顾,并通过问卷调查进行了调查。

结果

在曾经结婚并尝试生育的男性中,单侧隐睾男性中无法生育子女的比例(10.5%)显著高于对照组(5.4%)。在比较两组从无避孕措施的规律性交到第一个孩子受孕的持续时间时,未发现差异。睾丸固定术的年龄或生活方式因素与生育能力之间没有关系,睾丸固定术的年龄与从规律无保护性交到受孕的月数之间也没有关系。两组的生育能力均与女性相关的不孕因素以及精索静脉曲张的存在有关。

结论

与对照组相比,单侧隐睾后生育能力受到损害。单侧组的不孕发生率约为对照组的两倍。在有生育能力的亚组中,没有证据表明存在需要更长时间无避孕规律性交才能受孕的亚生育情况。未发现睾丸固定术的年龄与生育能力之间存在相关性。

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