Lee P A, O'Leary L A, Songer N J, Bellinger M F, LaPorte R E
Department of Pediatrics, University of Pittsburgh School of Medicine, Children's Hospital of Pittsburgh, USA.
Br J Urol. 1995 Jun;75(6):704-7. doi: 10.1111/j.1464-410x.1995.tb07375.x.
To determine whether paternity is decreased among men who were formerly unilaterally or bilaterally cryptorchid and to ascertain whether paternity is related to their age at orchidopexy.
Men who underwent orchidopexy between 1955 and 1969 at the Children's Hospital of Pittsburgh (363) and a group of age-matched control men (336) were surveyed by questionnaire and their medical records reviewed.
Of the married men, significantly more of the unilateral cryptorchid (75%) and control (76%) groups had fathered children than had the bilateral cryptorchid group (P < 0.005). Furthermore, when the groups were compared during the period of regular intercourse with no contraception until conception of their first child, the bilateral group had relatively fewer conceptions during the first year and more after the first year. When the unilateral and bilateral groups were analysed separately, there was no relationship between either age at orchidopexy and paternity or between the age at orchidopexy and the duration of regular unprotected intercourse before conception.
Compared with a control group, paternity was compromised after bilateral, but not unilateral, cryptorchidism. Age at orchidopexy was not correlated with paternity.
确定曾患单侧或双侧隐睾症的男性其生育能力是否下降，并确定生育能力是否与其睾丸固定术时的年龄有关。
通过问卷调查对1955年至1969年间在匹兹堡儿童医院接受睾丸固定术的男性（363例）以及一组年龄匹配的对照男性（336例）进行调查，并查阅他们的病历。
在已婚男性中，单侧隐睾组（75%）和对照组（76%）生育子女的人数明显多于双侧隐睾组（P<0.005）。此外，当比较这些组在无避孕措施的规律性交直至第一个孩子受孕期间的情况时，双侧隐睾组在第一年的受孕次数相对较少，而在第一年之后较多。当分别分析单侧和双侧隐睾组时，睾丸固定术时的年龄与生育能力之间以及睾丸固定术时的年龄与受孕前规律无保护性交的持续时间之间均无关联。
与对照组相比，双侧隐睾症后生育能力受损，而单侧隐睾症则不然。睾丸固定术时的年龄与生育能力无关。
