Ndip R N, Obi M C, Obi C L, Nwawolo C, Igumbor E O, Obi A A
Faculty of Science, Microbiology Unit, University of Lagos, Akoka, Nigeria.
Afr J Med Med Sci. 1995 Dec;24(4):353-7.
A total of one hundred and two cases of otitis media were screened for the isolation of bacterial flora of ears. Out of this, Staphylococcus aureus, Streptococcus pneumoniae and Haemophilus influenzae accounting for 41.2%, 25.5% and 13.3% respectively were isolated. A further two hundred and four sputum samples from cases of lower respiratory tract infections were screened. Moraxella catarrhalis, S. aureus, S. pneumoniae and H. influenzae constituting 20.9%, 37%, 30% and 21% were isolated in that order. Thirty-one point seven percent of the Moraxella catarrhalis isolates were beta-lactamase positive. Beta-lactamase M. catarrhalis were resistant to penicillin and ampicillin while the non-beta-lactamase producers were sensitive to these antimicrobial agents. However, both beta-lactamase producers and non-producers were resistant to trimethoprim but sensitive to erythromycin, tetracycline and amoxycillin. Staphylococcus aureus, S. pneumoniae and H. influenzae was also sensitive to penicillin while S. pneumoniae was also sensitive to erythromycin and H. influenzae to chloramphenicol.
共对102例中耳炎患者进行耳部细菌菌群分离筛选。其中，分离出的金黄色葡萄球菌、肺炎链球菌和流感嗜血杆菌分别占41.2%、25.5%和13.3%。另外，对204例下呼吸道感染患者的痰液样本进行了筛选。依次分离出卡他莫拉菌、金黄色葡萄球菌、肺炎链球菌和流感嗜血杆菌，分别占20.9%、37%、30%和21%。31.7%的卡他莫拉菌分离株β-内酰胺酶呈阳性。产β-内酰胺酶的卡他莫拉菌对青霉素和氨苄西林耐药，而不产β-内酰胺酶的菌株对这些抗菌药物敏感。然而，产β-内酰胺酶菌株和不产β-内酰胺酶菌株均对甲氧苄啶耐药，但对红霉素、四环素和阿莫西林敏感。金黄色葡萄球菌、肺炎链球菌和流感嗜血杆菌对青霉素敏感，肺炎链球菌对红霉素敏感，流感嗜血杆菌对氯霉素敏感。
