Blomstrand P, Kongstad O, Broqvist M, Dahlström U, Wranne B
Department of Clinical Physiology, Linköping Heart Centre, University of Linköping, Sweden.
Clin Physiol. 1996 Sep;16(5):483-93. doi: 10.1111/j.1475-097x.1996.tb01014.x.
Mitral and pulmonary venous flow velocity recordings are often used for the assessment of left ventricular diastolic function. These curves are, however, also influenced by other factors. To investigate whether mitral annulus motion carries additional information in this context, mitral annulus motion was compared to Doppler registrations of mitral and pulmonary flow velocities in 38 patients with heart failure (NYHA II-III) after myocardial infarction. Patients with an increased atrial contribution to mitral annulus motion (> 57%, n = 12) had a higher mitral late-to-early flow velocity ratio (A/E) and pulmonary systolic to diastolic filling ratio (< 0.01). Patients with atrial displacement above average for the group (> or = 5.1 mm, n = 19) had a higher mitral (A/E) ratio and pulmonary systolic to diastolic filling ratio than patients with a lower than average atrial component (P < 0.05). There was a significant correlation between a/T ratio and A/E ratio (r = 0.61, P < 0.001) and between pulmonary flow and transmitral flow (= 0.76, P < 0.001). We conclude that an increased atrial displacement of the mitral annulus is a frequent finding in patients with signs of left ventricular relaxation abnormality. There is a significant correlation between a/T ratio and A/E ratio but the information contained in the two indices are not identical.
二尖瓣和肺静脉血流速度记录常用于评估左心室舒张功能。然而，这些曲线也受其他因素影响。为了研究在此背景下二尖瓣环运动是否携带额外信息，对38例心肌梗死后心力衰竭（纽约心脏协会II - III级）患者的二尖瓣环运动与二尖瓣和肺血流速度的多普勒记录进行了比较。心房对二尖瓣环运动贡献增加（> 57%，n = 12）的患者，其二尖瓣舒张晚期与早期血流速度比值（A/E）和肺收缩期与舒张期充盈比值更高（< 0.01）。心房移位高于该组平均水平（≥ 5.1 mm，n = 19）的患者，其二尖瓣（A/E）比值和肺收缩期与舒张期充盈比值高于心房成分低于平均水平的患者（P < 0.05）。a/T比值与A/E比值之间存在显著相关性（r = 0.61，P < 0.001），肺血流与经二尖瓣血流之间也存在显著相关性（= 0.76，P < 0.001）。我们得出结论，二尖瓣环心房移位增加在有左心室舒张异常迹象的患者中很常见。a/T比值与A/E比值之间存在显著相关性，但两个指标所含信息并不相同。
