Wandt B, Bojö L, Tolagen K, Wranne B
Department of Clinical Physiology, Central Hospital, S-651 85 Karlstad, Sweden.
Heart. 1999 Aug;82(2):192-8. doi: 10.1136/hrt.82.2.192.
To investigate the value of Simpson's rule, Teichholz's formula, and recording of mitral ring motion in assessing left ventricular ejection fraction (EF) in patients with left ventricular hypertrophy.
Left ventricular ejection fraction calculated by Simpson's rule and by Techholz's formula and estimated by mitral ring motion was compared with values obtained by radionuclide angiography.
Secondary referral centre.
16 patients with left ventricular hypertrophy and a clinical diagnosis of hypertrophic cardiomyopathy or hypertension.
Calculation by Teichholz's formula overestimated left ventricular ejection fraction by 10% (p = 0.002) and estimation based on mitral ring motion-that is, long axis measurements-underestimated ejection fraction by 19% (p = 0.002), without significant correlation between ring motion and ejection fraction. There was no significant difference between mean values of ejection fraction calculated by Simpson's rule and measured by the reference method, but a considerable scatter about the regression line with a standard error of the estimate of 9.3 EF%.
In patients with left ventricular hypertrophy the ejection fraction, calculated by Teichholz's formula or Simpson's rule, is a poor measure of left ventricular function. When mitral ring motion is used for the assessment in these patients the function should be expressed in ways other than by the ejection fraction.
探讨Simpson法则、Teichholz公式及二尖瓣环运动记录在评估左心室肥厚患者左心室射血分数（EF）中的价值。
将通过Simpson法则和Teichholz公式计算以及通过二尖瓣环运动估算得出的左心室射血分数与放射性核素血管造影获得的值进行比较。
二级转诊中心。
16例左心室肥厚且临床诊断为肥厚型心肌病或高血压的患者。
Teichholz公式计算结果高估左心室射血分数10%（p = 0.002），基于二尖瓣环运动（即长轴测量）的估算结果低估射血分数19%（p = 0.002），且环运动与射血分数之间无显著相关性。Simpson法则计算的射血分数平均值与参考方法测量值之间无显著差异，但回归线周围存在较大离散度，估计标准误为9.3 EF%。
在左心室肥厚患者中，用Teichholz公式或Simpson法则计算的射血分数不能很好地衡量左心室功能。当使用二尖瓣环运动对这些患者进行评估时，不应仅用射血分数来表示其功能。
