Bayram M
Atatürk Universitesi Fen-Edebiyat Fakültesi, Matematik Bölümü Erzurum, Turkey.
Comput Biol Med. 1996 Sep;26(5):401-8. doi: 10.1016/0010-4825(96)00011-x.
In this paper we apply computer algebra techniques to analyze the control of metabolic networks. For this purpose, a computer program based on metabolic control theory was developed. When a stoichiometry matrix of the metabolic networks is given, the program calculates all the control coefficients (flux and metabolic control coefficients, summation and connectivity relationships) using elasticity coefficients. The program can be applied to any metabolic network which includes unlimited steps and intermediate metabolites.
在本文中,我们应用计算机代数技术来分析代谢网络的控制。为此,开发了一个基于代谢控制理论的计算机程序。当给出代谢网络的化学计量矩阵时,该程序使用弹性系数计算所有的控制系数(通量和代谢控制系数、求和与连通性关系)。该程序可应用于任何包含无限步骤和中间代谢物的代谢网络。