Eugene J, Goldstone J, Moore W S
Ann Surg. 1977 Aug;186(2):177-83. doi: 10.1097/00000658-197708000-00009.
A 15-year experience with 92 subcutaneous arterial bypass grafts for lower extremity revascularization has been reviewed. Fifty-nine AF and 33 FF bypass operations were performed on 89 patients whose average age was 66 years. The overall five-year survival was 33% compared to an expected survival of 80%. 88% of the AF, and 76% of the FF operations were performed for limb salvage, bypass of an aortic aneurysm, or replacement of an infected aortic graft. The remainder were performed for intermittent claudication on patients who were too ill to withstand an intra-abdominal operation. 75% of the patients with AF grafts and 64% of those with FF grafts experienced complete relief of lower extremity ischemia, including all of the patients with claudication. Graft patency was analyzed by the life table method. In the FF series, 74% of the grafts remained patent for one year; 73% for two years; 66% for three years; and 53% for four years. A 50% incidence of thrombosis occurred at the end of two years in the AF group. The patency rate of the AF grafts was also studied with regard to the type of graft material employed: a 50% incidence of thrombosis was reached at 36 months with knitted Dacron; at 18 months with weave-knit Dacron; and at 9 months with woven Dacron. THESE DATA INDICATE THAT: (1) contrary to our previous report, weave-grafts provide adequate blood flow to the lower extremities but do not remain patent as long as more conventional types of reconstruction; (2) subcutaneous grafts should be performed only when an intra-abdominal procedure is contraindicated or life expectancy is limited.
回顾了92例用于下肢血管重建的皮下动脉旁路移植术的15年经验。对89例平均年龄为66岁的患者进行了59例腋股(AF)和33例股股(FF)旁路手术。总体五年生存率为33%,而预期生存率为80%。88%的AF手术和76%的FF手术是为了挽救肢体、绕过主动脉瘤或更换感染的主动脉移植物而进行的。其余手术是为了给病情过重无法耐受腹腔内手术的间歇性跛行患者进行的。75%接受AF移植物的患者和64%接受FF移植物的患者下肢缺血症状完全缓解,包括所有间歇性跛行患者。采用寿命表法分析移植物通畅情况。在FF组中,74%的移植物在1年内保持通畅;73%在2年内保持通畅;66%在3年内保持通畅;53%在4年内保持通畅。AF组在两年末血栓形成发生率为50%。还研究了AF移植物通畅率与所用移植物材料类型的关系:针织涤纶在36个月时血栓形成发生率为50%;编织针织涤纶在18个月时血栓形成发生率为50%;机织涤纶在9个月时血栓形成发生率为50%。这些数据表明:(1)与我们之前的报告相反,编织移植物可为下肢提供足够的血流,但不能像更传统的重建类型那样长期保持通畅;(2)仅当腹腔内手术禁忌或预期寿命有限时才应进行皮下移植物手术。