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白细胞抗原的系统发育保守表位

Phylogenetically conserved epitopes of leukocyte antigens.

作者信息

Vilmos P, Kurucz E, Ocsovszki I, Keresztes G, Andó I

机构信息

Institute of Genetics, Hungarian Academy of Sciences, Szeged, Hungary.

出版信息

Vet Immunol Immunopathol. 1996 Aug;52(4):415-26. doi: 10.1016/0165-2427(96)05595-x.

DOI:10.1016/0165-2427(96)05595-x
PMID:8896233
Abstract

The occurrence of conserved epitopes in the immune system was investigated on the leukocytes of cattle, river buffalo, sheep, camel, swine and humans by indirect immunofluorescence and flow cytometry. The distribution of the most conservative epitopes on leukocyte sub-populations suggests that the expression pattern of the proteins is similar. Western blotting experiments indicate that the recognized antigens are structural homologues.

摘要

通过间接免疫荧光和流式细胞术,对牛、水牛、绵羊、骆驼、猪和人类的白细胞进行研究,以探讨免疫系统中保守表位的出现情况。最保守表位在白细胞亚群上的分布表明,这些蛋白质的表达模式相似。蛋白质印迹实验表明,所识别的抗原是结构同源物。

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