Meyer J R, Roychowdhury S, Russell E J, Callahan C, Gitelman D, Mesulam M M
Department of Radiology, Northwestern University Medical School, Chicago, III., USA.
AJNR Am J Neuroradiol. 1996 Oct;17(9):1699-706.
To determine whether relative cortical thickness measurements of the precentral and postcentral gyri can be used to differentiate the central sulcus from adjacent cortical sulci.
Turbo inversion-recovery MR imaging of the entire brain was done with scans parallel to the anterior commissure-posterior commissure line. Cortical thickness was measured in each hemisphere with a jeweler's eyepiece with 0.1-mm gradations. Three measurements were obtained perpendicular to the central, precentral, and superior frontal sulci, as determined by means of established anatomic methods. The ratios of cortical thickness on both sides of the central, precentral, and superior frontal sulci were calculated and compared.
The mean ratio of precentral/postcentral gyri was 1.64 for the right hemisphere and 1.53 for the left hemisphere. The mean cortical thickness ratios were as follows: 1.01 for the right hemisphere and 3.01 for the left hemisphere across the precentral sulcus, and 1.03 for the right hemisphere and 0.99 for the left hemisphere across the superior frontal sulcus.
Cortical thickness measurements across the central sulcus provide a method for locating the primary motor (precentral gyri) and primary somatosensory (postcentral gyri) cortices. The higher mean cortical thickness ratio across the central sulcus corresponds with known cytoarchitectonic relationships.
确定中央前回和中央后回的相对皮质厚度测量值是否可用于区分中央沟与相邻皮质沟。
对全脑进行快速自旋回波反转恢复磁共振成像，扫描平行于前连合-后连合线。使用刻度为0.1毫米的珠宝商用目镜测量每个半球的皮质厚度。通过既定的解剖学方法确定，垂直于中央沟、中央前沟和额上沟进行三次测量。计算并比较中央沟、中央前沟和额上沟两侧的皮质厚度比值。
右半球中央前回/中央后回的平均比值为1.64，左半球为1.53。平均皮质厚度比值如下：右半球跨过中央前沟为1.01，左半球为3.01；右半球跨过额上沟为1.03，左半球为0.99。
测量中央沟两侧的皮质厚度为定位初级运动皮质（中央前回）和初级躯体感觉皮质（中央后回）提供了一种方法。中央沟两侧较高的平均皮质厚度比值与已知的细胞构筑关系相符。
