Gamble J A, Moore J, Lamki H, Howard P J
Br J Obstet Gynaecol. 1977 Aug;84(8):588-91. doi: 10.1111/j.1471-0528.1977.tb12659.x.
A 10 mg dose of diazepam was given intravenously to mothers at 15 to 205 minutes before delivery, and plasma diazepam concentrations were measured by gas-liquid chromatography in mothers and infants at delivery and again 24 hours later. The plasma levels in the infants were always significantly higher than in the mothers but there was no evidence to suggest that the newborn were unable to metabolize the drug. All infants had a good Apgar score at birth.
在分娩前15至205分钟给母亲静脉注射10毫克地西泮，通过气液色谱法在分娩时及24小时后测定母亲和婴儿血浆中的地西泮浓度。婴儿的血浆水平始终显著高于母亲，但没有证据表明新生儿无法代谢该药物。所有婴儿出生时阿氏评分良好。
