Roberts J A, Widjayanti S, Estuningsih E
Balai Penelitian Veterinar, Bogor, West Java, Indonesia.
Parasitol Res. 1996;82(8):743-6. doi: 10.1007/s004360050196.
Merino sheep acquired resistance against Fasciola gigantica, which is contrary to previous observations of infections with F. hepatica in that breed. The acquired resistance was manifest against young adult parasites. St. Croix sheep had previously been shown to have more resistance than European sheep against F. hepatica after primary infection; however, in F. gigantica infections in the present study there was no difference between the resistance levels of the breeds. Antigenic analysis of the host:parasite relationships could lead to identification of protective antigens suitable for use as vaccines.
美利奴羊获得了对巨片吸虫的抗性，这与之前该品种感染肝片吸虫的观察结果相反。这种获得性抗性在针对年轻成虫阶段的寄生虫时表现明显。圣克罗伊羊先前已被证明在初次感染后比欧洲羊对肝片吸虫具有更强的抗性；然而，在本研究中对巨片吸虫的感染中，这两个品种的抗性水平并无差异。对宿主与寄生虫关系进行抗原分析可能会鉴定出适合用作疫苗的保护性抗原。
