多氧霉素（核苷肽类抗生素）的生物合成：5-O-氨基甲酰-2-氨基-2-脱氧-L-木糖酸（氨基甲酰多氧氨酸）的生物合成途径。 - Suppr

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Biosynthesis of the polyoxins, nucleoside peptide antibiotics: biosynthetic pathway for 5-O-carbamoyl-2-amino-2-deoxy-L-xylonic acid (carbamoylpolyoxamic acid).

作者信息

Funayama S, Isono K

出版信息

Biochemistry. 1977 Jul 12;16(14):3121-7. doi: 10.1021/bi00633a013.

DOI:10.1021/bi00633a013

PMID:889792

Abstract

摘要

相似文献

Biosynthesis of the polyoxins, nucleoside peptide antibiotics: biosynthetic pathway for 5-O-carbamoyl-2-amino-2-deoxy-L-xylonic acid (carbamoylpolyoxamic acid).多氧霉素（核苷肽类抗生素）的生物合成：5-O-氨基甲酰-2-氨基-2-脱氧-L-木糖酸（氨基甲酰多氧氨酸）的生物合成途径。

Biochemistry. 1977 Jul 12;16(14):3121-7. doi: 10.1021/bi00633a013.

Biosynthesis of the polyoxins, nucleoside peptide antibiotics: glutamate as an origin of 2-amino-2-deoxy-L-xylonic acid (polyoxamic acid).

Biochemistry. 1975 Dec 30;14(26):5568-. doi: 10.1021/bi00697a005.

Origin of nitrogen in the biosynthesis of carbamoylpolyoxamic acid.氨甲酰聚草氨酸生物合成中氮的来源。

Biomed Mass Spectrom. 1978 Jan;5(1):89-90. doi: 10.1002/bms.1200050118.

Nature's combinatorial biosynthesis and recently engineered production of nucleoside antibiotics in Streptomyces.链霉菌中核苷类抗生素的自然组合生物合成及近期的工程化生产

World J Microbiol Biotechnol. 2017 Apr;33(4):66. doi: 10.1007/s11274-017-2233-6. Epub 2017 Mar 4.

An ATP-Dependent Ligase with Substrate Flexibility Involved in Assembly of the Peptidyl Nucleoside Antibiotic Polyoxin.一种依赖于 ATP 的具有底物柔性的连接酶，参与肽核苷抗生素多氧霉素的组装。

Appl Environ Microbiol. 2018 Jun 18;84(13). doi: 10.1128/AEM.00501-18. Print 2018 Jul 1.

Biosynthesis of the polyoxins, nucleoside peptide antibiotics: a new metabolic role for L-isoleucine as a precursor for 3-ethylidene-L-azetidine-2-carboxylic acid (polyoximic acid).多氧霉素（核苷肽类抗生素）的生物合成：L-异亮氨酸作为3-亚乙基-L-氮杂环丁烷-2-羧酸（多氧肟酸）前体的新代谢作用。

Biochemistry. 1975 Jul;14(13):2992-6. doi: 10.1021/bi00684a031.

Nucleoside antibiotics. VI. Biosynthesis of the pyrrolopyrimidine nucleoside antibiotic toyocamycin by Streptomyces rimosus.核苷类抗生素。VI. 龟裂链霉菌合成吡咯并嘧啶核苷类抗生素丰加霉素的生物合成。

Biochemistry. 1970 Mar 3;9(5):1260-6. doi: 10.1021/bi00807a030.

Biosynthesis of streptothricin antibiotics. IV. On the incorporation of L-arginine into streptolidine moiety by Streptomyces lavendulae OP-2.链丝菌素类抗生素的生物合成。IV. 淡紫色链霉菌OP-2将L-精氨酸掺入链霉胍部分的研究。

Chem Pharm Bull (Tokyo). 1977 May;25(5):1161-3. doi: 10.1248/cpb.25.1161.

Nucleoside antibiotics. Biosynthesis of arabinofuranosyladenine by Streptomyces antibioticus.

Biochemistry. 1972 Feb 29;11(5):911-6. doi: 10.1021/bi00755a034.

Nucleoside antibiotics. Biosynthesis of the maleimide nucleoside antibiotic, showdomycin, by Streptomyces showdoensis.核苷类抗生素。浅间链霉菌合成马来酰亚胺核苷类抗生素——浅间霉素。

Biochemistry. 1971 Sep 14;10(19):3608-14. doi: 10.1021/bi00795a019.

引用本文的文献

Identification and characterization of enzymes involved in the biosynthesis of pyrimidine nucleoside antibiotics.鉴定和表征嘧啶核苷抗生素生物合成中的酶。

Nat Prod Rep. 2021 Jul 21;38(7):1362-1407. doi: 10.1039/d0np00064g.

Genetic dissection of the polyoxin building block-carbamoylpolyoxamic acid biosynthesis revealing the "pathway redundancy" in metabolic networks.遗传剖析多杀菌素结构单元——氨甲酰聚多氨酸生物合成揭示代谢网络中的“途径冗余”。

Microb Cell Fact. 2013 Dec 7;12:121. doi: 10.1186/1475-2859-12-121.

Characterization of the polyoxin biosynthetic gene cluster from Streptomyces cacaoi and engineered production of polyoxin H.可可链霉菌多氧霉素生物合成基因簇的表征及多氧霉素H的工程生产。

J Biol Chem. 2009 Apr 17;284(16):10627-38. doi: 10.1074/jbc.M807534200. Epub 2009 Feb 20.

An adenosine triphosphate-dependent carbamoylphosphate--3-hydroxymethylcephem O-carbamoyltransferase from Streptomyces clavuligerus.来自棒状链霉菌的一种依赖三磷酸腺苷的氨甲酰磷酸 - 3 - 羟甲基头孢菌素O - 氨甲酰转移酶。

Biochem J. 1980 Mar 1;185(3):555-64. doi: 10.1042/bj1850555.

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