Ghanadian R, Auf G, Chisholm G D, O'Donoghue E P
Br J Urol. 1978 Dec;50(7):567-9. doi: 10.1111/j.1464-410x.1978.tb06213.x.
The suitability of an exchange assay with methyltrienolone (R1881) for the measurement of androgen receptors in human prostatic tumours has been investigated. Having established the specificity of this compound for androgen receptor assay, a pilot study was carried out to measure dihydrotestosterone (DHT) receptor in 27 cases of benign hypertrophy and 18 cases of malignant tumour of the prostate.
已对用甲基三烯醇酮(R1881)进行交换分析以测定人前列腺肿瘤中雄激素受体的适用性进行了研究。在确定该化合物对雄激素受体分析的特异性后,开展了一项初步研究,以测定27例良性前列腺增生和18例前列腺恶性肿瘤中的双氢睾酮(DHT)受体。