HIV阴性患者的播散性隐球菌病
Disseminated cryptococcosis in HIV negative patient.
作者信息
Hassoun Ali, Mehrotra Neha
机构信息
Department of Infectious Diseases, Alabama Infectious Diseases Center, Huntsville, Alabama, USA.
出版信息
BMJ Case Rep. 2018 May 12;2018:bcr-2017-223500. doi: 10.1136/bcr-2017-223500.
Abstract
A 52-year-old white diabetic male with 4-weeks history of persistent cough followed by headache, drenching night sweats, low-grade fever, worsening photophobia, nausea and vomiting was presented. Examination was significant for photophobia and diminution of vision. His spinal fluid and blood cultures were positive for Intravenous fluconazole were given for 2 weeks followed by oral fluconazole. There was significant improvement in systemic and ocular symptoms. HIV serology was negative, but his CD4 counts were low with inverted CD4:CD8 ratio.
摘要
一名52岁的白人糖尿病男性患者，有持续咳嗽4周的病史，随后出现头痛、盗汗、低热、畏光加重、恶心和呕吐。检查发现有畏光和视力减退。他的脑脊液和血培养显示[具体病原体]阳性。给予静脉注射氟康唑2周，随后口服氟康唑。全身和眼部症状有显著改善。HIV血清学检查为阴性，但他的CD4细胞计数低，CD4:CD8比值倒置。
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