Korabiowska M, Brinck U, Mirecka J, Kellner S, Marx D, Schauer A
Department of Pathology, Georg-August University Göttingen, Germany.
In Vivo. 1995 Sep-Oct;9(5):433-8.
121 cases of cutaneous melanomas, 82 lymph nodes with melanoma metastases and 62 naevi were stained immunohistochemically for presence of Ki-67 antigen and c-myc oncogene. A significant correlation between expression of investigated markers, and survival time as well as presence of metastases, in cutaneous melanomas was found (p < 0.05). The role of Ki-67 antigen for differential diagnosis between naevi and melanomas is also demonstrated.
对121例皮肤黑色素瘤、82个有黑色素瘤转移的淋巴结和62个痣进行免疫组织化学染色，以检测Ki-67抗原和c-myc癌基因的存在情况。发现在皮肤黑色素瘤中，所研究标志物的表达与生存时间以及转移情况之间存在显著相关性（p<0.05）。还证实了Ki-67抗原在痣与黑色素瘤鉴别诊断中的作用。
