Nagasawa T, Yoshizawa F, Nishizawa N
Department of Bioscience and Technology, Iwate University, Japan.
Biosci Biotechnol Biochem. 1996 Mar;60(3):501-2. doi: 10.1271/bbb.60.501.
Urinary excretion of N tau-methylhistidine (MeHis) in rats was linearly elevated by starvation for 2 days. Plasma concentration of MeHis on day 1 and day 2 of starvation were increased 2.4- and 2.6-fold, respectively. The amount of released MeHis from the isolated muscles into medium during a 2-h incubation period was increased with starvation corresponded to the plasma MeHis concentration. The results of this study suggest that plasma MeHis is a sensitive index of myofibrillar protein degradation.
