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中脑和下丘脑刺激诱导的厌恶性和欲求性效应(作者译)

[Aversive and appetitive effects induced by mesencephalic and hypothalamic stimulation (author's transl)].

作者信息

Schmitt P, Abou-Hamed H

出版信息

Brain Res. 1977 Jul 22;130(3):521-30. doi: 10.1016/0006-8993(77)90113-5.

Abstract

Approach and escape latencies induced by hypothalamic or central grey stimulation were measured in the rat by means of a shuttle-box technique. In order to compare the effects obtained at various brain sites, the maximal value of the escape latency/approach latency ratio was determined within a given range of stimulation intensities. The ratio was shown to have high values at sites located in the ventral part of the central grey (in or near the dorsal raphe nucleus) or in the lateral hypothalamus. It was equal to zero for most of the sites located in the dorsal part of the central grey, as the rate regularly interrupted the stimulation without initiating it again. Intermediate values were obtained at sites located in the medial hypothalamus and in the dorsal pontine tegmentum.

摘要

通过穿梭箱技术测量大鼠下丘脑或中脑导水管周围灰质刺激诱发的趋避潜伏期。为了比较在不同脑区获得的效应,在给定的刺激强度范围内确定逃避潜伏期/趋近潜伏期比值的最大值。结果显示,在中脑导水管周围灰质腹侧部分(在中缝背核内或附近)或下丘脑外侧的部位,该比值较高。对于中脑导水管周围灰质背侧部分的大多数部位,该比值等于零,因为大鼠通常会中断刺激而不再重新启动。在内侧下丘脑和脑桥背侧被盖的部位获得了中间值。

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