Smith R J, Burke D K, Sato Y, Poust R I, Kimura K, Bauman N M
Department of Otolaryngology, University of Iowa, Iowa City, USA.
Arch Otolaryngol Head Neck Surg. 1996 Nov;122(11):1195-9. doi: 10.1001/archotol.1996.01890230041009.
To assess the efficacy of OK-432 sclerotherapy in the treatment of lymphangiomas.
Nonrandomized trial; follow-up, 4 to 29 months.
Academic tertiary referral medical center.
Six children with presumed lymphangiomas; age range at initial treatment, 1 month to 7 years 10 months.
Fluoroscopically guided cyst aspiration, cystography, and injection of OK-432.
Clinical and radiographic comparisons before and after therapy.
Complete response in 2 macrocystic lymphangiomas; no response in 3 microcystic lymphangiomas; and no response in 1 venous malformation.
OK-432 sclerotherapy may be effective treatment for macrocystic lymphangiomas.
评估沙培林硬化疗法治疗淋巴管瘤的疗效。
非随机试验；随访4至29个月。
学术性三级转诊医疗中心。
6例疑似淋巴管瘤患儿；初始治疗时年龄范围为1个月至7岁10个月。
在荧光镜引导下进行囊肿抽吸、囊肿造影及注射沙培林。
治疗前后的临床及影像学对比。
2例大囊型淋巴管瘤完全缓解；3例微囊型淋巴管瘤无反应；1例静脉畸形无反应。
沙培林硬化疗法可能是治疗大囊型淋巴管瘤的有效方法。
