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罕见却值得关注:成人型颈淋巴管瘤——我们的经验及综合综述

Rare Yet Relevant: Adult Onset Cervical Lymphangioma - Our Experience and Comprehensive Review.

作者信息

Singh Charu, Zaidi Ariba

机构信息

Dr. Ram Manohar Lohia Institute of Medical sciences, Lucknow, Uttar Pradesh India.

出版信息

Indian J Otolaryngol Head Neck Surg. 2024 Oct;76(5):4979-4985. doi: 10.1007/s12070-024-04869-4. Epub 2024 Jul 18.

DOI:10.1007/s12070-024-04869-4
PMID:39376344
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11455978/
Abstract

Cervical lymphangiomas are anomalies that arise from lymphatic vessels, characterized by gradual and painless growth. While predominantly located in the neck, they may also manifest in the axilla, mediastinum, groin, and abdominal organs. Cervical lymphangioma usually occurs in children and is relatively rare in adults. The purpose of this study was to investigate the characteristics of cervical lymphangiomas in adults. We reviewed the medical records and analysed clinical data obtained from fifteen adult patients who suffered from cervical lymphangioma and were operated from January 2021 to January 2023. Out of 15 cases, 73.3% were females and 26.7% were males. All tumours were unilaterally located. Five patients had prior history of associated dyspnoea / dysphagia. All 15 cervical lymphangiomas (100%) were adjacent to the carotid sheath .Tumour size ranged from 6 cm to 15 cm, with the maximum diameter of ≥ 15 cm in two cases, between 6 cm and 10 cm in eight cases and less than 6 cm in five cases. Further, in this study all cervical lymphangiomas were surgically excised. Postoperative courses were uneventful, and histo-pathological examinations confirmed all cases to be cystic lymphangiomas. A 6 -month follow-up in all 15 cases showed no recurrences. Overall, this study underscores the importance of a multidisciplinary approach involving clinicians, radiologists, and surgeons in the management of adult cervical lymphangiomas, with an emphasis on accurate diagnosis, appropriate classification, and tailored treatment strategies to optimize patient outcomes and minimize complications.

摘要

颈部淋巴管瘤是起源于淋巴管的异常病变,其特点是生长缓慢且无痛。虽然主要位于颈部,但也可能出现在腋窝、纵隔、腹股沟和腹部器官。颈部淋巴管瘤通常发生于儿童,在成人中相对少见。本研究的目的是调查成人颈部淋巴管瘤的特征。我们回顾了15例2021年1月至2023年1月期间接受手术治疗的成人颈部淋巴管瘤患者的病历并分析了临床资料。15例患者中,73.3%为女性,26.7%为男性。所有肿瘤均为单侧发病。5例患者有既往呼吸困难/吞咽困难病史。所有15例颈部淋巴管瘤(100%)均毗邻颈动脉鞘。肿瘤大小从6cm至15cm不等,其中2例最大直径≥15cm,8例在6cm至10cm之间,5例小于6cm。此外,本研究中所有颈部淋巴管瘤均接受了手术切除。术后病程平稳,组织病理学检查证实所有病例均为囊性淋巴管瘤。15例患者均进行了6个月的随访,未见复发。总体而言,本研究强调了临床医生、放射科医生和外科医生多学科协作在成人颈部淋巴管瘤管理中的重要性,重点在于准确诊断、恰当分类和量身定制治疗策略,以优化患者预后并减少并发症发生。

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本文引用的文献

1
Mesenteric cystic lymphangioma in an adult: An unusual case report.成人肠系膜囊性淋巴管瘤:一例罕见病例报告。
Ann Med Surg (Lond). 2022 Jun 4;78:103917. doi: 10.1016/j.amsu.2022.103917. eCollection 2022 Jun.
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Cervical lymphangioma in adults: A report of seven cases and review of the literature.成人颈部淋巴管瘤:7例报告并文献复习
Laryngoscope Investig Otolaryngol. 2022 Apr 22;7(3):751-756. doi: 10.1002/lio2.801. eCollection 2022 Jun.
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Genetic and Molecular Determinants of Lymphatic Malformations: Potential Targets for Therapy.淋巴管畸形的遗传和分子决定因素:潜在治疗靶点
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4
Cervical Cystic Lymphangiomas in Adults: A Case Series of a Rare Entity with Literature Review.成人宫颈囊状淋巴管瘤:一种罕见实体的病例系列报告并文献复习。
Head Neck Pathol. 2021 Jun;15(2):503-508. doi: 10.1007/s12105-020-01227-y. Epub 2020 Sep 21.
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Cystic lymphangioma in adult: a case report and a review of the literature.成人囊性淋巴管瘤:一例报告并文献复习
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6
Adult-onset giant cervical cystic hygroma with pressure manifestations on aerodigestive tract, managed surgically: reporting of a rare case.成人期巨大颈部囊状水瘤伴气道消化道受压表现,手术治疗:1例罕见病例报告
Ann R Coll Surg Engl. 2019 Mar;101(3):e84-e87. doi: 10.1308/rcsann.2018.0214. Epub 2019 Jan 3.
7
Sudden Onset, Rapidly Expansile, Cervical Cystic Hygroma in an Adult: A Rare Case with Unusual Presentation and Extensive Review of the Literature.成人突发性、快速扩张性颈部囊状水瘤:1例表现异常的罕见病例及文献综述
Case Rep Otolaryngol. 2017;2017:1061958. doi: 10.1155/2017/1061958. Epub 2017 May 24.
8
Treatment options of lymphangioma circumscriptum.局限性淋巴管瘤的治疗选择。
Indian Dermatol Online J. 2015 Jul-Aug;6(4):293-4.
9
Imaging features of cervical lymphangiomas as a cause of respiratory distress and vascular-lymphatic disturbance.作为呼吸窘迫和血管-淋巴系统紊乱病因的颈部淋巴管瘤的影像学特征。
Eurasian J Med. 2009 Apr;41(1):39-43.
10
Cervical cystic lymphangioma in an adult, diagnosed on FNAC.经细针穿刺抽吸活检(FNAC)诊断的成人颈部囊性淋巴管瘤。
J Cytol. 2009 Oct;26(4):164-5. doi: 10.4103/0970-9371.62191.