Chukanov V I, Kuz'mina N V
Probl Tuberk. 1996(1):17-9.
Spontaneous rosette formation with sheep red cells, lymphocyte blast-transformation in the presence of PHA and PPD, estimation of cells carrying CD3+, CD4+, CD8+, EKK-antigens were studied in 208 HIV-negative adult patients with destructive tuberculosis of the lungs. The sputum from 87 of them contained M. tuberculosis sensitive to antituberculous drugs. M. tuberculosis from 121 of them were resistant to drugs. It was found that patients discharging drug-resistant M. tuberculosis had significantly more frequent suppression of T-cell immunity than patients whose M. tuberculosis were sensitive to chemotherapy.
在208例患有肺部破坏性肺结核的HIV阴性成年患者中，研究了与绵羊红细胞的自发玫瑰花结形成、在PHA和PPD存在下的淋巴细胞转化、携带CD3 +、CD4 +、CD8 +、EKK抗原的细胞的评估。其中87例患者的痰液中含有对抗结核药物敏感的结核分枝杆菌。其中121例患者的结核分枝杆菌对药物耐药。结果发现，排出耐药结核分枝杆菌的患者比其结核分枝杆菌对化疗敏感的患者T细胞免疫抑制更为频繁。
