Kondo H, Suzuki K, Takagi I, Miyamoto N, Baba S, Kobayashi T, Yokota A, Tanaka I, Sugiyama K
Department of Otolaryngology, Nagoya City University Medical School, Japan.
Acta Otolaryngol Suppl. 1996;525:64-7.
Surface and tissue transitional concentration of 3% FOM aerosol for treatment of paranasal sinusitis was examined in 18 patients (21 sides) who underwent the Caldwell-Luc operation. In this operation, patients have a bony window on the sinus; we therefore investigated the difference of compliance of the maxillary sinus between when we closed the bony window with subcutaneous tissue and when we did it with a silicone sheet before the FOM nebulization. No significance was found in the mean concentration of FOM either at the maxillary sinus surface or in the tissue with or without the use of the silicone sheet. We also examined the concentration using a jet-type nebulizer and an ultra-sonic type nebulizer. Using the ultrasonic-type nebulizer resulted in a higher transitional concentration at two sites of the maxillary sinus surface than when using the jet-type nebulizer. The results suggest that the ultrasonic-type nebulizer is more effective in the treatment of paranasal sinusitis than the jet-type, and that there was no change of maxillary sinus compliance with or without a bony window.
在18例（21侧）接受柯-陆氏手术的患者中，检测了用于治疗鼻窦炎的3%福尔马林气雾剂的表面和组织过渡浓度。在该手术中，患者鼻窦处有一个骨窗；因此，我们研究了在福尔马林雾化前，用皮下组织封闭骨窗和用硅胶片封闭骨窗时上颌窦顺应性的差异。使用或不使用硅胶片时，上颌窦表面或组织中福尔马林的平均浓度均无显著差异。我们还使用喷射式雾化器和超声式雾化器检测了浓度。与使用喷射式雾化器相比，使用超声式雾化器时上颌窦表面两个部位的过渡浓度更高。结果表明，超声式雾化器在治疗鼻窦炎方面比喷射式雾化器更有效，并且有无骨窗时上颌窦的顺应性没有变化。
