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胆囊切除术后胆管损伤:49例采用不同治疗方式的经验

Postcholecystectomy bile duct injuries: experience with 49 cases managed by different therapeutic modalities.

作者信息

Abdel Wahab M, el-Ebiedy G, Sultan A, el-Ghawalby N, Fathy O, Gad el-Hak N, Abo Elenin A, Abo Zid M, Ezzat F

机构信息

Gastroenterology Surgical Center, Mansoura University, Mansoura, Egypt.

出版信息

Hepatogastroenterology. 1996 Sep-Oct;43(11):1141-7.

PMID:8908542
Abstract

BACKGROUND/AIMS: In this study we present our experience in the management of iatrogenic biliary injuries. Forty-nine cases with iatrogenic biliary injuries were managed in our center during the period from 1984 to 1995.

MATERIAL AND METHODS

Forty patients were referred from other hospitals after cholecystectomy, and 9 cases underwent the original operation in our center. Four (0.3%) of our patients after 1300 conventional cholecystectomy, and 5 (0.9%) cases after 550 laparoscopic cholecystectomy.

RESULTS

The injuries were recognized intraoperatively in 5 (10%) cases and were immediately repaired, 3 cases by axial anastomosis and T-tube drainage, 2 cases by hepatico-jejunostomy (Roux-en-Y). The injuries were detected in the remaining 44 patients postoperatively from one week up to 2 months, the mode of presentation was jaundice in 39 (89%) cases, biliary fistula with or without jaundice and biliary peritonitis were detected in 13 (30%) and in 4 (9%) cases respectively. Eleven (25%) cases were treated endoscopically by sphincterotomy, stent in 8 cases, dilatation and double stent in two cases, and dilatation using rigid dilators and stent in one case. The remaining 33 (75%) cases were treated surgically by hepatico-jejunostomy in 21 (64%) cases, and hepatico-duodenostomy in 12 (36%) cases. No hospital mortality occurred, but late mortality occurred in two (5%) patients after surgery due to biliary restricture with progressive cirrhosis in one case, and due to advanced colon cancer in the other case, an din one (9%) case after endoscopic treatment. We achieved 87% excellent surgical results during the period of follow-up (36 months), while 80% excellent results were achieved after endoscopic treatment. Good final results (95%, 83%) were achieved after hepatico-jejunostomy and after hepatico-duodenostomy respectively.

CONCLUSION

Postcholecystectomy biliary injuries present a surgical problem needing extra efforts and careful management. Hepatico-jejunostomy appears to be the procedure of choice in repairing these injuries. Immediate surgical repair of bile duct injury offers excellent results with lower morbidity rates. Endoscopic treatment may be a less invasive technique and have a role in some types of injuries, but needs more time for accurate evaluation.

摘要

背景/目的:在本研究中,我们介绍了处理医源性胆管损伤的经验。1984年至1995年期间,我们中心共处理了49例医源性胆管损伤病例。

材料与方法

40例患者是在胆囊切除术后从其他医院转诊而来,9例在我们中心接受了初次手术。在1300例传统胆囊切除术后有4例(0.3%)发生损伤,在550例腹腔镜胆囊切除术后有5例(0.9%)发生损伤。

结果

5例(10%)损伤在术中被发现并立即进行了修复,3例采用轴向吻合和T管引流,2例采用肝空肠吻合术(Roux-en-Y)。其余44例患者在术后1周直至2个月内发现损伤,表现为黄疸的有39例(89%),有或无黄疸的胆瘘和胆汁性腹膜炎分别在13例(30%)和4例(9%)中被发现。11例(25%)患者接受了内镜下括约肌切开术治疗,8例放置支架,2例进行扩张并放置双支架,1例使用硬式扩张器扩张并放置支架。其余33例(75%)患者接受了手术治疗,21例(64%)采用肝空肠吻合术,12例(36%)采用肝十二指肠吻合术。无医院死亡病例,但术后有2例(5%)患者发生晚期死亡,1例因胆管狭窄伴进行性肝硬化,另1例因晚期结肠癌,内镜治疗后有1例(9%)死亡。在随访期(36个月)内,手术治疗的优良率为87%,内镜治疗后为80%。肝空肠吻合术和肝十二指肠吻合术后分别取得了良好的最终效果(95%,83%)。

结论

胆囊切除术后胆管损伤是一个需要付出额外努力并谨慎处理的外科问题。肝空肠吻合术似乎是修复这些损伤的首选方法。胆管损伤的立即手术修复效果良好,发病率较低。内镜治疗可能是一种侵入性较小的技术,在某些类型的损伤中发挥作用,但需要更多时间进行准确评估。

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