Yamao K, Mizutani S, Nakazawa S, Inui K, Kanemaki N, Miyoshi H, Segawa K, Zenda H, Kato T
Department of Internal Medicine, Second Teaching Hospital, Fujita Health University, School of Medicine.
Hepatogastroenterology. 1996 Sep-Oct;43(11):1238-45.
BACKGROUND/AIMS: It is important to achieve detection of of anomalous connections of the pancreatobiliary ducts (ACPBD), because this condition often leads to pancreatobiliary disease. The present prospective investigation focused on revealing the incidence of ACPBD in asymptomatic individuals undergoing medical checkups.
Extracorporeal ultrasonography (US) was performed on all asymptomatic individuals undergoing medical checkups. Identification by abdominal ultrasonography of 3 mm or more gallbladder wall thickening, or 10 mm or more dilatation of the bile duct were considered indicative of ACPBD and endoscopic ultrasonography (EUS) was carried out in selected cases. Endoscopic retrograde cholangiopancreatography (ERCP) was then performed to confirm the existence of ACPBD.
The overall incidence of ACPBD was 0.03% (9/27,076 subjects). ACPBD was found in 23% of cases with bile duct dilatation, and in 2.9% with gallbladder wall thickening.
ACPBD was not as rare a disease as expected. For early detection of ACPBD, identification by abdominal ultrasonography of gallbladder wall thickening or dilatation of the bile duct are indicative. Patients who are suspected of having this abnormality should then undergo EUS. The final diagnosis should then be made by ERCP.
背景/目的：检测胰胆管异常连接（ACPBD）很重要，因为这种情况常导致胰胆疾病。本前瞻性研究聚焦于揭示在接受体检的无症状个体中ACPBD的发生率。
对所有接受体检的无症状个体进行体外超声检查（US）。腹部超声检查发现胆囊壁增厚3mm或以上，或胆管扩张10mm或以上被视为ACPBD的指征，并对部分病例进行内镜超声检查（EUS）。然后进行内镜逆行胰胆管造影（ERCP）以确认ACPBD的存在。
ACPBD的总体发生率为0.03%（27076例受试者中有9例）。在胆管扩张的病例中，23%发现有ACPBD，在胆囊壁增厚的病例中，2.9%发现有ACPBD。
ACPBD并非像预期那样罕见。为早期检测ACPBD，腹部超声检查发现胆囊壁增厚或胆管扩张具有指征意义。怀疑有这种异常的患者应随后接受EUS检查。最终诊断应由ERCP做出。
