Malley D S, Barone R, Heinemann M H
Department of Ophthalmology, New York Hospital-Cornell Medical Center, New York, USA.
Am J Ophthalmol. 1996 Nov;122(5):731-2. doi: 10.1016/s0002-9394(14)70496-9.
To report treatment of bilateral cytomegalovirus (CMV) retinitis in an 11-year-old girl with acquired immunodeficiency syndrome (AIDS).
Case report describing the use of intravitreal ganciclovir sustained-release devices to treat CMV retinitis, involving zones 1 through 3, which progressed despite single and combination intravenous therapy with ganciclovir and foscarnet.
Stabilization with no active CMV retinitis was achieved after bilateral implantation of intravitreal sustained-release ganciclovir devices. There was no reactivation of the retinitis during the 5 months of follow-up.
Sustained-release ganciclovir implants can be used to achieve local control of CMV retinitis in the pediatric patient.
报告一名11岁获得性免疫缺陷综合征（AIDS）女孩双侧巨细胞病毒（CMV）视网膜炎的治疗情况。
病例报告，描述使用玻璃体内更昔洛韦缓释装置治疗CMV视网膜炎，病变累及1至3区，尽管采用更昔洛韦和膦甲酸钠单一及联合静脉治疗，病情仍进展。
双侧植入玻璃体内更昔洛韦缓释装置后，CMV视网膜炎无活动，病情稳定。随访5个月期间视网膜炎未复发。
更昔洛韦缓释植入物可用于实现对儿童患者CMV视网膜炎的局部控制。
