Ueda M, Ueki M
Department of Obstetrics and Gynecology, Osaka Medical College, Japan.
Int J Gynaecol Obstet. 1996 Oct;55(1):59-65. doi: 10.1016/0020-7292(96)02718-x.
The clinical characteristics of ovarian tumors associated with pregnancy were investigated.
A series of 106 cases of ovarian tumor surgically resected during pregnancy was investigated with respect to incidence, clinicopathologic features and outcome.
Among 106 cases undergoing ovarian surgery, 31 (29.2%), 70 (66%) and five (4.7%) were diagnosed as physiologic, benign and malignant, respectively. The incidence of benign neoplastic tumor was 1:112 deliveries and that of malignant neoplastic tumor was 1:1684 deliveries. Dermoid cyst was the most common lesion found. Of the 70 benign tumors, 51 (72.9%) were greater than 8 cm in diameter and 55 (78.6%) were preoperatively diagnosed before the 10th gestational week; 44 (62.9%) were operated before the 15th gestational week. The spontaneous abortion rate in 80 cases followed up after surgery was only 10%, 61 patients (76.3%) progressing to full-term delivery. Five malignant tumors included three epithelial carcinomas, one embryonal carcinoma and one dysgerminoma.
Ovarian surgery in the first trimester for persistent or enlarging masses is important to obtain a final histologic diagnosis and rule out malignancy.
