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妊娠期巨大恶性卵巢肿瘤:两例报告。

Large malignant ovarian tumors during pregnancy: two cases.

机构信息

Gynecological and Obstetrical Department, Women's Hospital, School of Medicine, Zhejiang University, Hangzhou, People's Republic of China.

出版信息

Onco Targets Ther. 2014 Nov 17;7:2121-5. doi: 10.2147/OTT.S69799. eCollection 2014.

DOI:10.2147/OTT.S69799
PMID:25484595
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4240190/
Abstract

The present study reports two cases of large ovarian malignancy during pregnancy, which is very rare. The two patients were received between Nov 2012 and Feb 2013 at Gynecological and Obstetrical Department, Women's Hospital, School of Medicine, Zhejiang University (People's Republic of China). Both cases present tumor sized more than 20 cm, with one case of 40 cm. Both patients underwent timely cesarean section, with survival of the Child, and successful removal of the tumor. All patients showed good outcome in the follow-up period. Therefore the large ovarian malignancy during pregnancy could be well treated after careful clinical evaluation.

摘要

本研究报道了两例妊娠期间发生的罕见大型卵巢恶性肿瘤。这两例患者均于 2012 年 11 月至 2013 年 2 月在浙江大学医学院附属妇产科医院妇产科接受治疗。两例肿瘤均大于 20cm,其中一例为 40cm。两例患者均及时行剖宫产术,成功娩出患儿,同时完整切除肿瘤。所有患者在随访期间均预后良好。因此,经过仔细的临床评估,妊娠期间的大型卵巢恶性肿瘤可以得到很好的治疗。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aaed/4240190/97f04e64229e/ott-7-2121Fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aaed/4240190/97f04e64229e/ott-7-2121Fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aaed/4240190/97f04e64229e/ott-7-2121Fig1.jpg

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本文引用的文献

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Surgical management of adnexal masses in pregnancy.孕期附件肿块的手术治疗
JSLS. 2014 Jan-Mar;18(1):71-5. doi: 10.4293/108680813X13693422521007.
2
Ovarian cancer complicated by pregnancy: Analysis of 10 cases.妊娠合并卵巢癌:10例分析
Oncol Lett. 2012 Mar;3(3):577-580. doi: 10.3892/ol.2011.545. Epub 2011 Dec 29.
3
Serum levels of the ovarian cancer biomarker HE4 are decreased in pregnancy and increase with age.血清中卵巢癌标志物 HE4 的水平在妊娠期间降低,并随年龄增长而升高。
Am J Obstet Gynecol. 2012 Apr;206(4):349.e1-7. doi: 10.1016/j.ajog.2011.12.028. Epub 2011 Dec 30.
4
Chemotherapy in pregnancy.孕期化疗
Clin Obstet Gynecol. 2011 Dec;54(4):602-18. doi: 10.1097/GRF.0b013e318236e9f9.
5
Metastatic bilateral malignant ovarian tumors associated with pregnancy.与妊娠相关的双侧转移性恶性卵巢肿瘤。
Taiwan J Obstet Gynecol. 2011 Sep;50(3):405-6; author reply 407. doi: 10.1016/j.tjog.2011.01.036.
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Ovarian cancer during pregnancy.妊娠期卵巢癌。
Int J Gynaecol Obstet. 2011 Nov;115(2):140-3. doi: 10.1016/j.ijgo.2011.05.025. Epub 2011 Aug 26.
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Risk of torsion and malignancy by adnexal mass size in pregnant women.孕妇附件包块大小与扭转和恶变风险。
Acta Obstet Gynecol Scand. 2011 Apr;90(4):358-61. doi: 10.1111/j.1600-0412.2011.01070.x. Epub 2011 Mar 4.
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Stage I ovarian cancer cases during early, mid and late pregnancy periods: three case reports and review of the literature.妊娠早期、中期和晚期的Ⅰ期卵巢癌病例:三例报告及文献综述
J Obstet Gynaecol Res. 2011 Jun;37(6):650-5. doi: 10.1111/j.1447-0756.2010.01412.x. Epub 2010 Dec 15.
9
Ovarian cancer during pregnancy: clinical and pregnancy outcome.妊娠期卵巢癌:临床和妊娠结局。
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Ovarian tumors associated with pregnancy: a 20-year experience in a teaching hospital.妊娠相关卵巢肿瘤:一家教学医院 20 年的经验。
Arch Gynecol Obstet. 2010 Nov;282(5):529-33. doi: 10.1007/s00404-009-1346-z. Epub 2010 Jan 5.