Hayashi T, Mine M, Kojima S, Sekine H
Department of Urology, University Hospital, Mizonokuchi, Japan.
Urol Int. 1996;57(3):194-6. doi: 10.1159/000282911.
We here present a patient with an extragonadal germ cell tumor followed by a metachronous testicular tumor 7 years later. The histological findings of the extragonadal tumor and the subsequent testicular tumor were quite different; the former was of a mixed type with teratoma, embryonal carcinoma and yolk sac tumor, and the latter a pure seminoma. Such a long clinical time lag as 7 years and the histological differences between the two tumors suggest that they occurred independently. To our knowledge, this may be the first case report in the literature, in which a testicular tumor occurred metachronously after extragonadal tumor extirpation.
我们在此报告一例性腺外生殖细胞肿瘤患者,7年后出现异时性睾丸肿瘤。性腺外肿瘤和随后的睾丸肿瘤的组织学表现截然不同;前者为畸胎瘤、胚胎癌和卵黄囊瘤的混合型,后者为纯精原细胞瘤。长达7年的临床时间间隔以及两种肿瘤之间的组织学差异表明它们是独立发生的。据我们所知,这可能是文献中首例关于性腺外肿瘤切除术后异时性发生睾丸肿瘤的病例报告。