Gillies W E, Brooks A M
Clinic 3, Royal Victorian Eye and Ear Hospital, East Melbourne.
Aust N Z J Ophthalmol. 1996 Aug;24(3):169-87. doi: 10.1111/j.1442-9071.1996.tb01579.x.
We have investigated the vascular perfusion of a wide variety of conditions of the anterior segment using fluorescein angiography.
The conditions were classified and findings reported according to the system set out below. Patients underwent full ocular examination. Fluorescein angiography of the anterior segment was carried out when indicated to investigate iris atrophy and neovascularisation. Specular microscopy of the corneal endothelium was used to detect changes in this tissue.
The hypoperfusion was variable in degree and accompanied by varying degrees of iris hypoplasia and atrophy with neovascularisation. The degree of neovascularisation depended upon its rapidity of development, the pre-existing state of vascular perfusion and the underlying pathological condition.
Hypoperfusion with resultant ischaemia and neovascularisation is common in conditions of the anterior segment. An understanding of the changes is valuable in treating many conditions affecting the anterior segment. The changes observed may also occur elsewhere in the physical system and may be a significant part of the ageing process, either as scattered, disparate processes or as part of a general disease process.
我们使用荧光素血管造影术研究了眼前节多种情况的血管灌注。
根据以下所述系统对情况进行分类并报告研究结果。患者接受全面的眼部检查。当需要调查虹膜萎缩和新生血管形成时，进行眼前节荧光素血管造影。使用角膜内皮镜检查来检测该组织的变化。
灌注不足的程度各不相同，并伴有不同程度的虹膜发育不全、萎缩及新生血管形成。新生血管形成的程度取决于其发展速度、血管灌注的先前状态以及潜在的病理状况。
灌注不足导致的缺血和新生血管形成在眼前节疾病中很常见。了解这些变化对于治疗许多影响眼前节的疾病很有价值。观察到的这些变化也可能发生在身体系统的其他部位，并且可能是衰老过程的重要组成部分，无论是作为分散的、不同的过程还是作为一般疾病过程的一部分。
