Jones A W, Andersson L
Department of Forensic Toxicology, National Laboratory of Forensic Chemistry, University Hospital, Linköping, Sweden.
J Forensic Sci. 1996 Nov;41(6):916-21.
The ratio of blood-alcohol concentration (BAC) to breath-alcohol concentration (BrAC) was determined for 799 individuals apprehended for driving under the influence of alcohol (DUI) in Sweden. The BrAC was determined with an infrared analyzer (Intoxilyzer 5000S) and venous BAC was measured by headspace gas chromatography. The blood samples were always taken after the breath tests were made and the average time delay was 30 +/- 12 min (+/- SD), spanning from 6 to 60 min. The blood/breath ratios of alcohol decreased as the time between sampling blood and breath increased (F = 15.4, p < 0.001), being 2337 +/- 183 (6 to 15 min), 2302 +/- 202 (16 to 30 min), 2226 +/- 229 (31 to 45 min), and 2170 +/- 225 (46 to 60 min). When the BAC was corrected for the metabolism of alcohol at a rate of 0.019 g%/h, the mean blood/breath ratios were 2395 +/- 193 (6 to 15 min), 2416 +/- 211 (16 to 30 min), 2406 +/- 223 (31 to 45 min), and 2407 +/- 210 (45 to 60 min); no significant differences (F = 0.197, p > 0.05). The overall mean time-adjusted blood/breath ratio (+/- SD) was 2407 +/- 213 and the 95% limits of agreement (LOA) were 1981 and 2833. During 1992, 1993, and 1994, the mean blood/breath ratios of alcohol were remarkably constant, being 2409 +/- 288, 2407 +/- 206, and 2421 +/- 235, respectively, and the values were not significantly influenced by the person's age, gender, or blood-alcohol content. In 34 individuals (4.3%), the blood/breath ratio was less than 2100 after compensating for metabolism of alcohol between the times of sampling blood and breath. This compares with 156 individuals (19.6%) having a blood/breath ratio less than 2100:1 without making any correction for the metabolism of alcohol.
对瑞典799名因酒后驾车（DUI）而被捕的人员测定了血液酒精浓度（BAC）与呼气酒精浓度（BrAC）的比率。BrAC用红外分析仪（Intoxilyzer 5000S）测定，静脉血BAC通过顶空气相色谱法测量。血液样本总是在呼气测试后采集，平均时间延迟为30±12分钟（±标准差），范围从6到60分钟。酒精的血/气比率随着采血和呼气之间时间的增加而降低（F = 15.4，p < 0.001），分别为2337±183（6至15分钟）、2302±202（16至30分钟）、2226±229（31至45分钟）和2170±225（46至60分钟）。当以0.019 g%/小时的酒精代谢率校正BAC时，平均血/气比率分别为2395±193（6至15分钟）、2416±211（16至30分钟）、2406±223（31至45分钟）和2407±210（45至60分钟）；无显著差异（F = 0.197，p > 0.05）。总体平均时间校正血/气比率（±标准差）为2407±213，95%一致性界限（LOA）为1981和2833。在1992年、1993年和1994年期间，酒精的平均血/气比率非常稳定，分别为2409±288、2407±206和2421±235，这些值不受人的年龄、性别或血液酒精含量的显著影响。在34名个体（4.3%）中，在补偿采血和呼气之间的酒精代谢后，血/气比率低于2100。相比之下，有156名个体（19.6%）在未对酒精代谢进行任何校正的情况下血/气比率低于2100:1。
