Kostakoglu L, Wong J C, Barrington S F, Cronin B F, Dynes A M, Maisey M N
Clinical PET Centre, Division of Radiological Sciences, UMDS of Guy's and St. Thomas' Hospital, London, United Kingdom.
J Nucl Med. 1996 Nov;37(11):1771-3.
This study describes the physiological uptake of 18F-fluoro-2-deoxyglucose (FDG) by the laryngeal muscles secondary to activation of the patient's vocal folds and related laryngeal muscles during speech.
Twenty-four patients undergoing routine PET scans were randomized into two groups to ascertain the relationship between FDG uptake in the laryngeal region and speech. One group was assigned to talk and the other group remained silent during the injection and uptake period of FDG.
FDG uptake in the laryngeal muscles in the scans was correlated with speech. Patients who spoke continually during the uptake period had high-grade FDG uptake, those who spoke intermittently had low-grade uptake and those who remained silent had no detectable increase in FDG uptake in the region of the larynx.
The relationship between the degree of laryngeal muscle uptake and speech provides useful information to allow differentiation of physiological from pathological uptake in the neck.
本研究描述了在言语过程中，患者声带及相关喉部肌肉激活继发喉部肌肉对18F-氟-2-脱氧葡萄糖（FDG）的生理性摄取。
24例行常规PET扫描的患者被随机分为两组，以确定喉部区域FDG摄取与言语之间的关系。一组在FDG注射及摄取期间被要求说话，另一组保持沉默。
扫描中喉部肌肉的FDG摄取与言语相关。在摄取期间持续说话的患者有高度FDG摄取，间歇性说话的患者有低度摄取，而保持沉默的患者喉部区域未检测到FDG摄取增加。
喉部肌肉摄取程度与言语之间的关系为区分颈部生理性摄取与病理性摄取提供了有用信息。
