Barrington S F, Maisey M N
Clinical PET Center, University Medical School, Guys Hospital, London, United Kingdom.
J Nucl Med. 1996 Jul;37(7):1127-9.
We have observed a pattern of symmetrically increased uptake of [18F]fluorodeoxyglucose (FDG) in the neck and thoracic paravertebral regions of several patients referred for whole-body PET. The distribution is suggestive of uptake in contracting skeletal muscle in tense patients.
To test this hypothesis, six successive patients who exhibited this pattern of uptake underwent rescanning using an identical imaging protocol but with oral diazepam before injection of FDG.
The increased neck and paravertebral uptake was significantly reduced or abolished with diazepam, confirming the supposition that this increased neck and paravertebral uptake represents a normal variant of muscle uptake.
Oral diazepam, given before the uptake period can be helpful in such patients to exclude the masking of potential abnormalities by this characteristic pattern of FDG uptake.
我们在数名接受全身PET检查的患者颈部和胸段椎旁区域观察到[18F]氟脱氧葡萄糖（FDG）摄取呈对称性增加的模式。这种分布提示紧张患者收缩骨骼肌摄取增加。
为验证这一假设，对六名呈现这种摄取模式的连续患者，在注射FDG前口服地西泮，采用相同成像方案进行再次扫描。
地西泮使颈部和椎旁摄取增加显著减少或消失，证实颈部和椎旁摄取增加代表肌肉摄取的正常变异这一推测。
在摄取期前给予口服地西泮，有助于此类患者排除这种FDG摄取特征模式对潜在异常的掩盖。
