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育龄妇女风疹血清阳性率。

Seroprevalence of rubella in women of reproductive age.

作者信息

Yadav S, Gupta S, Kumari S

机构信息

Department of Obstetrics and Gynaecology, Safdarjang Hospital, New Delhi.

出版信息

Indian J Pathol Microbiol. 1995 Apr;38(2):139-42.

PMID:8919097
Abstract

This study was conducted on 160 females of childbearing age and 40 girls of prefertility age group. The rubella immunity status was analysed according to their age, social class, geographical distribution and previous obstetric history. History of previous rubella infection was obtained in 12% cases only. The over all incidence of rubella immunity was found to be 55%. There was a gradual increase in the immunity status, with peak incidence of 66% between 30 to 34 years of age. Females of low socioeconomic status showed higher incidence of immunity (63%) compared to social class I (40%). Rubella immunity was higher in urban female population (57%), where-as only 49% of rural females were immune to rubella virus infection. The immunity status of women with previous BOH was higher (61%) as compared to those with normal obstetric performance (54.6%). From the above observations, it was concluded that a substantial number of women enter child bearing without immunity to rubella. A simple HAI test for rubella antibody (IgG) can be a good pointer to pick up susceptible female population and the seronegative females should be immunised against rubella before they contemplate pregnancy.

摘要

本研究对160名育龄女性和40名育龄前期女孩进行。根据她们的年龄、社会阶层、地理分布和既往产科病史分析风疹免疫状况。仅在12%的病例中获得了既往风疹感染史。风疹免疫的总体发生率为55%。免疫状况呈逐渐上升趋势,30至34岁年龄组的发病率最高,为66%。社会经济地位较低的女性的免疫发生率(63%)高于社会阶层I的女性(40%)。城市女性人群的风疹免疫率较高(57%),而农村女性中只有49%对风疹病毒感染具有免疫力。有既往产科病史的女性的免疫状况(61%)高于产科情况正常的女性(54.6%)。根据上述观察结果得出结论,相当数量的女性在没有风疹免疫力的情况下进入生育期。一种简单的风疹抗体(IgG)血凝抑制试验可以很好地筛选出易感女性人群,血清阴性的女性在考虑怀孕前应接种风疹疫苗。

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