Mancia M, Marini G
Istituto di Fisiologia Umana II, Facolta di Medicina, Universita degli Studi, Italy.
Arch Ital Biol. 1995 Dec;134(1):65-80.
The excitotoxin ibotenic acid was injected bilaterally into the intralaminar centre median nucleus of chronically implanted cats in order to study the effects of early excitation of centre median population on electrographic correlates of behavioral states and to compare them to those induced by injection into intralaminar centralis lateralis nucleus, previously shown. Immediately and during the first 24h after injection, highly aroused behavior with electrocortical activation, myoclonic jerks, enhancement of ocular movements and ponto-geniculo-occipital waves were observed. Surprisingly, in contrast to the increase of REM sleep episodes in centralis lateralis cases, REM sleep was obliterated. The injection sites were histologically confirmed. The different connectional properties of the two intralaminar population may explain the differential results. 5. In conclusion, the present behavioral observations and electrographic findings taken together with the known afferent and efferent projections suggest that the caudal group of intralaminar nuclei is involved in orienting-like behavior.
为了研究中央中核早期兴奋对行为状态的脑电图相关指标的影响，并将其与先前在注射到外侧中央核时所诱导的影响进行比较，将兴奋性毒素鹅膏蕈氨酸双侧注射到长期植入电极的猫的中央中核内。在注射后即刻及最初24小时内，观察到伴有皮层电激活、肌阵挛性抽搐、眼球运动增强和桥脑-膝状体-枕叶波的高度觉醒行为。令人惊讶的是，与外侧中央核注射病例中快速眼动睡眠发作增加相反，快速眼动睡眠消失了。注射部位经组织学证实。两个板内核群不同的连接特性可能解释了不同的结果。5. 总之，目前的行为观察和脑电图结果，连同已知的传入和传出投射，表明板内核的尾侧组参与了类似定向的行为。
