Marini G, Gritti I, Mancia M
Istituto di Fisiologia Umana II, Milan, Italy.
Neurosci Lett. 1988 Jul 8;89(3):259-64. doi: 10.1016/0304-3940(88)90536-8.
Bilateral ibotenic acid lesions of the thalamic medialis dorsalis nucleus in chronically implanted cats produced a significant reduction of slow wave sleep. Rapid eye movement sleep was also affected but in a less significant manner. The lesions were limited to the intermediate portion of the nucleus, which receives projections from the brainstem and prosencephalic structures implicated in sleep mechanisms. These results are consistent with the hypothesis that the medialis dorsalis nucleus plays an important role in the induction and maintenance of sleep.
在长期植入电极的猫中，丘脑背内侧核的双侧鹅膏蕈氨酸损伤导致慢波睡眠显著减少。快速眼动睡眠也受到影响，但程度较轻。损伤局限于该核的中间部分，该部分接受来自与睡眠机制有关的脑干和前脑结构的投射。这些结果与背内侧核在睡眠诱导和维持中起重要作用的假设一致。
