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印度女性宫颈癌中特定类型人乳头瘤病毒(HPV)DNA的检测

Detection of type specific human papillomavirus (HPV) DNA in cervical cancers of Indian women.

作者信息

Chatterjee R, Roy A, Basu S

机构信息

Department of Tumor Virology, Chittaranjan National Cancer Institute, Calcutta, India.

出版信息

Indian J Pathol Microbiol. 1995 Jan;38(1):33-42.

PMID:8919467
Abstract

Commercial Vira Pap and Vira Type kits of Life Technologies Inc., U.S.A., were used to determine prevalence and type specific distribution of human papilloma viruses (HPV) in 18 biopsy samples of cervical carcinomas and 26 specimens of exfoliated cervical cells (swabs). The women were either attending out-patient's department of a suburban hospital or a cancer hospital in Calcutta, India. HPV DNA was detected in 9 biopsy specimens but not in any of the cervical swabs. Five of the 9 HPV positive biopsies had HPV DNA type 16/18. Neither HPV 6/11 nor HPV 31/33/35 DNAs were detected in any of these 9 specimens. Results indicated possible presence of HPV DNAs of types other than the above in at least 4 specimens.

摘要

美国生命技术公司的商用Vira Pap和Vira Type试剂盒,用于确定18份宫颈癌活检样本和26份宫颈脱落细胞样本(拭子)中人类乳头瘤病毒(HPV)的流行率及型别特异性分布。这些女性来自印度加尔各答一家郊区医院或一家癌症医院的门诊部。在9份活检样本中检测到了HPV DNA,但在任何宫颈拭子中均未检测到。9份HPV阳性活检样本中有5份含有HPV 16/18型DNA。在这9份样本中均未检测到HPV 6/11型或HPV 31/33/35型DNA。结果表明,至少有4份样本中可能存在上述以外型别的HPV DNA。

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引用本文的文献

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Vaccines against human papilloma virus and cervical cancer: an overview.人乳头瘤病毒疫苗与宫颈癌:概述
Indian J Community Med. 2008 Jul;33(3):143-5. doi: 10.4103/0970-0218.42045.