Sharma S, Nath P, Srivastava A N, Singh K M
Department of Pathology and Surgery, King George's Medical College, Lucknow, India.
Indian J Pathol Microbiol. 1995 Jan;38(1):55-62.
Twenty five cases of Wilms' tumour were studied with special reference to their morphological variations. Wilms' tumour constituted 7.6% of all the malignant tumours of childhood and 50% of renal malignancies. Male/female ratio was 4:1; the mean age being 3.5 years. Left side was commonly involved (60.9%) center dot bilateral involvement in one case (4.3%). Morphologic study revealed triphasic pattern in 60% cases, biphasic (epithelial + stromal) in 12% and monophasic pattern in 28%. Other features observed were myxomatous degeneration, rhabdomyoblasts, calcification and squamous epithelial pearls seen in 20%, 12%, 8% and 4% respectively.
对25例肾母细胞瘤进行了研究，特别关注其形态学变异。肾母细胞瘤占儿童所有恶性肿瘤的7.6%，占肾恶性肿瘤的50%。男女比例为4:1；平均年龄为3.5岁。左侧受累较为常见（60.9%），1例双侧受累（4.3%）。形态学研究显示，60%的病例为三相型，12%为双相型（上皮+间质），28%为单相型。观察到的其他特征分别为黏液样变性、横纹肌母细胞、钙化和鳞状上皮珠，分别见于20%、12%、8%和4%的病例。
