Smith B L, Cummings M C, Benes S, McCormack W M
Department of Medicine and of Obstetrics, State University of New York Health Science Center at Brooklyn 11203, USA.
Sex Transm Dis. 1996 Mar-Apr;23(2):127-30. doi: 10.1097/00007435-199603000-00007.
Previous studies have shown that self-inserted vaginal tampons can be used to obtain specimens for detection of Neisseria gonorrhoeae. There is a need to expand testing for infection with Chlamydia trachomatis to women who do not undergo regular gynecologic examinations.
To compare self-inserted tampons with clinician-obtained endocervical swabs for collection of samples to be examined for chlamydial infection.
Women referred because of recently detected untreated chlamydial infection inserted a vaginal tampon. Two endocervical swabs were obtained after the tampon was removed. One swab was cultured for Chlamydia trachomatis. The other swab and the tampon were examined with the Testpack Chlamydia antigen detection test.
Sixty-nine women were studied. Chlamydial infection was detected by culture in 75.4%, by Testpack (swab) in 63.8%, and by Testpack (tampon) in 52.2%.
Tampon-obtained specimens evaluated in the Testpack Chlamydia test were relatively insensitive. More sensitive tests for the detection of Chlamydia trachomatis infection with self-obtained specimens should be evaluated.
既往研究表明，自行置入的阴道棉塞可用于获取检测淋病奈瑟菌的标本。有必要将沙眼衣原体感染检测扩展至未定期进行妇科检查的女性。
比较自行置入的棉塞与临床医生获取的宫颈拭子在采集用于沙眼衣原体感染检测样本方面的情况。
因近期检测出未治疗的沙眼衣原体感染而前来就诊的女性置入阴道棉塞。取出棉塞后获取两根宫颈拭子。一根拭子用于沙眼衣原体培养。另一根拭子及棉塞采用衣原体检测试剂盒进行衣原体抗原检测。
对69名女性进行了研究。通过培养检测出沙眼衣原体感染的比例为75.4%，通过检测试剂盒（拭子）检测出的比例为63.8%，通过检测试剂盒（棉塞）检测出的比例为52.2%。
采用衣原体检测试剂盒对棉塞获取的标本进行评估时相对不敏感。应评估用于检测自行获取标本中沙眼衣原体感染的更敏感检测方法。
