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[感觉运动皮层治疗后联合伤害性刺激与杏仁核复合体刺激时的血流动力学]

[Hemodynamics during combined nociceptive stimulation and stimulation of the amygdaloid complex following treatment of the sensomotor cortex].

作者信息

Isakova L S, Danilov G E

出版信息

Fiziol Zh SSSR Im I M Sechenova. 1977 Jul;63(7):988-96.

PMID:892103
Abstract

In acute experiments on cats, changes of the arterial pressue (AP), intracardiac pressure (ICP), and of the blood flow rate following a nociceptive stimulus (NS), electrical stimulation of the lateral nucleus of amygdala (AL), and the combination of these stimuli before and after application of strychnine and potassium chloride on sensorimotor cortical area, were studied. After the application of strychnine and potassium chloride, the stimulation of AL produced weaker pressor reaction; while a nociceptive stimulus was followed by the same changes as in the intact cats. After the application of strychnine, combination of the AL stimulation and NS produced the increase of pressor reaction; while after the application of potassium chloride, the pressor reaction did not change at all or became weaker. After the application of strychnine, the blood flow rate response to the stimuli was similar to the control experiments; after the application of potassium chloride the blood flow rate decreased.

摘要

在对猫进行的急性实验中,研究了在感觉运动皮层区域应用士的宁和氯化钾前后,伤害性刺激(NS)、杏仁核外侧核(AL)电刺激以及这些刺激组合后动脉血压(AP)、心内压(ICP)和血流速率的变化。应用士的宁和氯化钾后,刺激AL产生的升压反应较弱;而伤害性刺激后的变化与完整猫相同。应用士的宁后,AL刺激和NS组合产生升压反应增加;而应用氯化钾后,升压反应完全不变或减弱。应用士的宁后,对刺激的血流速率反应与对照实验相似;应用氯化钾后,血流速率降低。

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